Although the antidepressant activity of justicia carnea has not been studied, and so may be hard to prove its efficacy scientifically, the leaves of justicia carnea have been used in traditional medicine to treat depression and anxiety disorder. Join now and start creating your dream garden! They range in colors such as red, orange, mauve, magenta, apricot, and pink. 10.9734/ijbcrr/2020/v29i630194. Nunes TRS, Cordeiro MF, Beserra FG, et al. Extraction was carried out by maceration (72h) following the method of Onoagbe et al., [13]. The species Justicia secunda Vahl belongs to the family - Acanthaceae - together with up to 600 other shrubs and herbs species. By entering your email address you agree to receive a daily email newsletter from Plant Care Today. The leaves of justicia carnea possess high content of iron and vitamin C. This compounds may be responsible for the blood boosting property of ewe eje leaves. Medapa S, Singh GRJ, Ravikumar V. The phytochemical and antioxidant screening of Justicia wynaadensis. J Med Plants Res. This plant is somewhat drought-tolerant once established but looks best with regular watering during periods of extended dry weather. Briefly, 1.0ml of the sample was mixed with 2ml of TCA-TBA-HCl reagent (0.37% thiobarbituric acid, 15% trichloroacetic acid and 0.24N HCl in 1:1:1) and boiled at 100C in a water bath for 15min. Gas chromatography/mass spectrometry of simple coumarins, 3-phenylpropionic acids and their hydroxy and methoxy derivatives. According to acute toxicity grading standards, LD50 of substances greater than 5000mg/kg is practically considered non-toxic [22, 23]. Consumption of medicinal plants has diverse therapeutic benefits and could also have toxic effect. The Brazilian Plume is native to mainly tropical areas in South America, meaning it thrives in warm and slightly humid climates. The flowers are slightly fragrant and mostly sterile. Pompella A, Visvikis A, Paolicchi A, De Tata V, Casini AF. [4].Inflammationinjuries, in an attempt to heal is presented by five cardinal signs of heat (calor), redness (rubor), swelling (tumor), pain (dolor) and loss of function5.Studieshave demonstrated inflammation as being caused by J. Pharmacogn. 2012;9(1):817 https://doi.org/10.4314/ajtcam.v9i1.12. There are several claims that justicia carnea can prevent epilepsy and convulsion among children. You can add the leaves and water altogether in a pot and allow to boil till the water turns red. Justicia carnea is commonly cultivated and grown as an ornamental potted plant. 2012; 22(1):220238; https://doi.org/10.1590/S0102-695X2011005000196. Justicia carnea does not cause miscarriage or congenital birth defects. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. J Ethnopharmacol. 2015;174:61827 https://doi.org/10.1016/j.jep.2015.06.005. Higher doses (>500mg/kg) of extract significantly (p<0.05) increased RBC, hemoglobin and platelet compared to the control. J Ethnopharmacol 2000;70(2):151-159. How often should it be watered? McCune LM, Johns T. Antioxidant activity in medicinal plants associated with the symptoms of diabetes mellitus used by the indigenous peoples of the north American boreal forest. Read also (Cashew leaves: health benefits and side effects of Anacardium occidentale). Ewe eje isn't capable of causing any side or negative effects if consumed moderately. Organic extract of Justicia pectoralis Jacq. 2015;6(7):265270. 3. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. National Research Council. Pinch Justicia carnea plants back after theyve flowered. This is why you should avoid potting them if you live in colder areas. https://doi.org/10.1016/j.jep.2007.02.011. Diallo A, Gbeassor M, Vovor A, Eklu-Gadegbeku K, Aklikokou K, Agbonon A. Furthermore, increased MID by the extracts could indicate macrophage formation ability and pathogenic scavenging role. The description of these plants has been written based on numerous outside resources. J Nat Prod 1988;51(3):599-600. https://doi.org/10.1016/j.biocel.2006.07.001. This study investigated the in-vitro antioxidant activity of ethanol leaf extract of Justicia carnea and its effect on antioxidant status of alloxan-induced diabetic albino rats. International Journal of Biochemistry Research & Review. The results of this study suggests that ethanol extract of J. carnea leaf is relatively safe, could be beneficial in alleviating hematology related abnormalities without causing adverse effects on endogenous antioxidant system. The aim of this study is to evaluate the safety of ethanol extract of J. carnea leaf assessing the hematology indices, organ antioxidant system and histology in healthy male wistar rats. There may be some problems if the air is too dry in winter. However, watch out for nematodes and spider mites. Relative to the control, liver of rats treated with doses of J. carnea ethanol extract showed varied degree of hepatic injury in a dose dependent manner. Biochem Pharmacol. The higher LD50 (>5000mg/kg body weight) of J. carnea leaf ethanol extract suggested that the ethanol extract is experimentally safe and not toxic. et al. Make sure to follow the package instructions carefully. Dyslipidemia is one of the risk factors of cardiovascular diseases. Article ID 687197, 2013; p. 13. https://doi.org/10.1155/2013/687197. The animals were allowed free access to rat chow and water ad libitum. A multidisciplinary overview of intoxicating snuff rituals in the western hemisphere. Photomicrograph of a liver sections stained with Haematoxylin and Eosin (Mag. Mr. E.S. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Eyong EU, Umoh IB, Ebong PE, Eteng MU, Antai AB, Akpa AO. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. The genus Justicia named after the 18th-century Scottish botanist James Justice is a flowering plant in the family Acanthaceae. Backfill the soil gently, filling the empty space around the root ball and then press it down with your hands. Exactly 1.0ml of tissues (liver and kidney) was deproteinised using 0.1ml of 10% TCA and centrifuged at 650g for 5min to obtain supernatant. African J Plant Sci. The liver and kidney of rats administered with 500mg/kg JCEE and above demonstrated slight increase in MDA level with significant (P<0.05) increase only observed in the liver of rats that received 1200mg/kg of extract. How Justicia Betonica is effective for various diseases is listed in repertory format. Be sure to follow relevant directions on product labels and consult your, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Mediterranean, Low-Fat Diets Are Best for Heart Problems, Least Amount of Exercise You Need to Stay Healthy, Nerve 'Pulse' Therapy May Help Ease Sciatica, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. The plant possess several bioactive compounds like polyphenols, which act as antioxidants or anti-inflammatory compounds. ESA conceived and designed the study. Rats in the 3 different groups received 10, 100 and 1000mg/kg body weight of JCEE orally using oral gavage. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. Local consumers of the leaves are mostly . Mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) showed significant (p<0.05) increased at 50mg/kg while doses greater than 100mg/kg showed no significant difference compared to the control. In this study, the aqueous leaf extract of Justicia carnea was used. What this means is that aside fighting anemia, justicia carnea leaves also improves your cardiovascular health by suppressing the tendency for dyslipidemia. I am a practicing medical doctor, a philosopher, critical thinker, a globalist, a patriot, SEO expert and a patient blogger. CAS J Am Diet Assoc. Mean lethal dose of the extract was found to be above 5000mg/kg body weight (bw). It results from one or more of the following events: loss of red blood cells (RBCs), reduction in the production of RBCs, increased destruction of RBCs, and shorter life span of RBCs (McEvoy, 2013). The unique and beautiful tubular flowers of Justicia carnea highlight the plant. Rather it can assist with improveing liver function such as detoxification. PubMed J Nat Prod 1988;51(4):804-805. It is cultivated and sold as a decorative potted plant and is planted in landscaping as a feature plant in warm . This information may not fit your specific health circumstances. Deleting this collection CANNOT be undone. It is nicknamed the Blood leaf, Blood of Jesus, and Jehovah Witness leaf in Nigeria, and is a widely used leaf across states in Nigeria. This could possibly indicate SOD stimulating effects of J. carnea leaf ethanol extract. This claim by traditional healers with regard to the efficacy of justicia carnea in the treatment diabetes have been researched on and it was found to be true. The haematological indices of the blood samples were determined using an automated URIT 2900 Plus 3 Differential Haematological Analyzer. Except the group that received 1200mg/kg JCEE which showed significant (p<0.05) elevation of SOD and MDA in the liver, other doses (<1200mg/kg) demonstrated no significant difference compared to the control. Also present in the leaf extract are minerals (such as magnesium, copper, iron, zinc, calcium); and vitamins (such as vitamins A, C, E and B-vitamins). Although, medically, it is advised you see your doctor or a physician before using the leaf for medicinal uses. Note: A=change in absorbance, TV=total volume, SV=sample volume, TP=total protein, =molar extinction =1.34104M1 cm1. Generic and epigenetic contributions to human nutrition and health: managing genome-diet interactions. Mr. K.O. J Ethnopharmacol 1999;64(3):265-270. Side effects of Ewe eje (Justicia carnea leaf Side Effects) Ewe eje is safe and healthy for consumption. Leal, L. K., Ferreira, A. Corroborating with the results of the antioxidant system and weight of the liver, continuous exposure to higher dose (1200mg/kg) of JCEE could result in hepatic damage. 2010;4(8):6804 https://doi.org/10.5897/JMPR09.487. But like in the case of depression and hepatitis, other species of justicia have been studied and proven to be antiepileptic. However, scientifically it is called Justicia carnea. Ewe eje improves the production of white blood cells and other antibodies, all which are essential for strengthening immunity. One of the side-effects of some orthodox drugs used in the past had been excessive inhibition of the carbohydrate-hydrolyzing enzymes, which in turn leads to abdominal discomfort and. Powdered sample was extracted using absolute ethanol and concentrated to obtain a slurry paste of J. carnea ethanol extracts. 1.3.1 Aetiologyof Anaemia Anaemia may be due to a single factor such as a nutritional deficiency or multifactorial (McEvoy, 2013). This lends the plant some interesting names such as Blood of Jesus plant and Hospital too far. Niger J Physiol Sci. 2013;3(4):1248 https://doi.org/10.7324/JAPS.2013.3422. Nutritional Composition of Ewe eje (Justicia carnea leaf). Phytochemical screening and Gas Chromatography-Mass Spectrometry (GC-MS) analysis indicated presence of . 2019;30(4):64554. Anaemia is a common blood disorder that affects people of all ages, though people at greater risk are the elderly, young women and infants. The concentration of reduced glutathione content of the tissues was estimated according to Sedlak and Lindsay [19] method. It is very rich in iron, a major component is RBC hemoglobin. Liver and kidney in all treated groups maintained similar activities of catalase (CAT) compared to the control. In which ever condition, the blood glucose level increases abnormally. Rats were routinely observed for signs of toxicity. Materials and Methods The possible anti-anaemic property of the leaf could be linked to the improved hemoglobin, PCV and RBC observed in this study. The aqueous leaf extract of ewe eje has demonstrated hypoglycaemic and antidiabetic properties; and thus, can be said to assist with blood sugar levels reduction. Research reports it isn't capable of . 1. View abstract. Biomed Environ Mass Spectrom 1988;15(8):413-417. The plant is transplanted in the spring. The package will tell you exactly how, when, and how much feed to use. The result from the kidney histology could be due to the presence of active secondary metabolites and daily dosing of the extract. Author ESA managed the literature searches and wrote the first draft of the manuscript with the assistant of FOA. Decoction of ewe eje or its leaf extract can lower serum cholesterol and get rid of bad cholesterol (LDL). View abstract. View abstract. A cup of ewe eje extract in the morning will provide you with energy needed to pull through the days activities. Terms and Conditions, Packed cell volume (PCV) and mean corpuscular volume (MCV) in treated rats with JCEE were statistically unperturbed compared to the control. In the study conducted by Onyeabor and his colleagues, it was shown that the leaf extract not only reverses anemic condition, but also lowered the lipid profile of the experimental rats. Biochemistry Unit, Department of Chemical Sciences, Olusegun Agagu University of Science and Technology, Okitipupa, Nigeria, Emmanuel Sina Akintimehin,Kayode Olayele Karigidi,Tope Samuel Omogunwa&Foluso Olutope Adetuyi, You can also search for this author in 2002;82:197205. Having discussed the nutritional benefits of ewe eje, i shall now take you through the various health benefits of justicia carnea leaves, and roots. 2. The liver and kidneys excised from all the experimental rats were fixed in a labeled sample bottles containing 10% formalin and processed for histological examination. The principle is based on the formation of coloured complex when protein peptide interacts with cupric ions in an alkaline medium. The Hematological system and antioxidant status of rats following 14days of sub-acute exposure tolerated the ethanol extract of J. carnea leaf. Acta Scientiarum Polonorum, Technologia Alimentaria. Justicia carnea is a medicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. It creates the perfect environment for aphids and dried sod. 2005 - 2023 WebMD LLC, an Internet Brands company. These animals were obtained from the animal house of the Department of Chemical Sciences, Ladoke Akintola University of Technology Ogbomoso Oyo State, Nigeria. Acute toxicity was determined in two phases using Lorke method. The reference cuvette contained 2.95ml buffer, 0.03ml of substrate (epinephrine) and 0.02ml of water. 400). Justicia carnea [jus-TEE-see-ah, KAR-nee-uh] is popularly known as the Brazilian Plume Flower. Tags: benefits of justicia carnea, health benefit of justicia carnea, justicia carnea . After 72h of soaking, the wine (dark purplish red) colored filtrate was filtered using a double cheese cloth, concentrated under reduced pressure using rotary evaporator and subsequently water bath at 40C to obtain a slurry (dark purple) extract termed Justicia carnea ethanol extract (JCEE). Free radicals and antioxidants in normal physiological functions and human disease. Ewe eje or Ewe ajeri is known by the Igbo tribe as Ogwu obara. Olaniyan JM, Hadiza LM, Hussaini AM, Musa BB, Abubakar SA. While histology of organs showed no adverse pathological lesions in the internal organs of rats, higher dose (1200mg/kg) over a period of time could cause noticeable liver and kidney injury. statement and Histopathological examination of liver and kidney showed mild to severe pathological lesion in a dose dependent manner. Each of the rats received 1500, 2900 and 5000mg/kg body weight of JCEE respectively and examined within 24h for manifestation of toxicity. Evid Based Complement Alternat Med. When properly cooked with water, the leaf resembles blood, and when milk is added, it turns pink. He has B.Sc.,and M.Sc. It is also composed of vitamins and minerals good for heart health. 2008;79:3326 https://doi.org/10.1016/j.fitote.2008.02.005. Catalase activity (U/ml) was measured following the method of Sinha [17]. At the end of 14th day of administration, rats were allowed to fast overnight, sacrificed to collect samples for biochemical analysis and histopathological examination. PubMed J Ethnopharmacol 1985;13(1):3-49. 15 Amazing benefits of brocoli juice and side effects. Inter J Biochem Cell Bio. The renal tubules and interstitial spaces appears distorted with presence of red inflammatory cells infiltrating the renal interstitial spaces as well as focal sclerosis of renal glomeruli with associated degeration of the glomerular membrane. Ashwagandha tea: 10 benefits, side effects and recipes, 7 interesting health facts about Black sapote fruits. 2007;112(1):13844. aqueous extract J. carnea leaves and its effects on haematological and some biochemical indices of anaemia induced male Wistar albino rats. It can be used to manage diabetes consition properly. The ability of glutathione to regenerate these dietary antioxidants has been linked to the redox state of glutathione disulphide-glutathione couple (GSSG/GSH) ratio [31]. Olumese FE, Onoagbe IO, Eze GI, Omoruyi FO. The weight of liver and kidney of rats were measured immediately after excising the organs and is presented in Table2. Mounanga MB, Mewonob L, Angone SA. Lipid peroxidation was determined by measuring the formation of thiobarbituric acid reactive substances (TBARS) according to the method described by Buege and Aust [20]. Side effects of Ewe eje (Justicia carnea leaf Side Effects). Braz. It is believed by local consumers in Ghana to possess anti-anaemic effects that boost blood levels in pregnant women, anaemic patients and also . Studies have shown that ewe eje isnt capable of causing damage to the liver. I do hope that after reading through this article, you would plan to start cultivating this amazing plant specie in your garden. Some people would rather chew the leaves, while others add to meals or brew into a tea (in combination with other plants). Saunders; 1995. p. 26873.

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